Mathew Street is a street in Liverpool, England, notable as the location of the Cavern Club, where The Beatles played on numerous occasions in their early career. It is the centre of the Mathew Street Festival, which fills the streets of Liverpool every summer.

Mathew Street is visited by thousands of tourists a year, who visit the Cavern Club and many surrounding attractions including a statue of John Lennon, a Beatles store and several pubs formerly frequented by The Beatles. A wall in Mathew Street is adorned by a sculpture by Arthur Dooley entitled "Four Lads Who Shook the World".